CHEM 4472 - Medicinal Chemistry II

3 Credit(s)

This course builds on Medicinal Chemistry I and introduces students to advanced topics in Medicinal Chemistry. The goal of this course is to give students a comprehensive overview of drug discovery, design, and development. Emphasis on lead identification, structure-activity relationships, pharmacokinetics, and pharmacodynamics will be key in this course. Students will learn how to identify liabilities in a molecule and how to optimize potency and selectivity against a target protein, enzyme or receptor. Students will be introduced to cheminformatics and QSAR approaches. Relevant case studies will be included to underline how these drug targets were eventually drugged using modern medicinal chemistry approaches. Throughout the course, students will integrate knowledge using specific industry examples with the goal to identify critical decision points in the drug design platform that eventually led to a new approved drug use.

Selective
Advanced Biology Selective. Advanced Chemistry Selective.
Prerequisite(s): CHEM 4471